Associate Professor Jia-Yi Zhang
Dr. Jiayi Zhang received her Ph.D. degree in physics from Brown University in 2009. From 2009 to 2011, she was a postdoctoral research associate in the Department of Neurobiology in Yale University. She received the Brown-Coxe fellowship during her postdoctoral training. She joined the institute of brain science in Fudan University at 2012.
The sensory world is organized into anatomically and functionally stereotypic maps in mammalian animals. Spontaneous neural activities exist early in development and play important roles in the development of such sensory maps. We are interested in understanding how neural activities affect the sensory map development using experimental techniques including optogenetics, in vivo electrophysiology, neuroanatmoy and genetic tools. We are also interested in learning how defects in neural activities lead to abnormal development of sensory maps and how to intervene and correct diseases caused by such defects. Our research currently uses the mouse visual maps as a model system, and the insights that we get from the visual system will be generalized to explore other sensory systems.
Address: Room. 1006, Mingdao Building,138 Yixueyuan Road, Institute of Brain Science, Fudan University, Shanghai China 200032
Lab website: http://homepage.fudan.edu.cn/jiayizhanglab/
1. Zhang Y, Qin N, Diao YP, Fan L, Guan YT, Crair MC, Zhang JY* (2012). Optogenetic tools for in vivo applications in neonatal mice.Nanosystems in Engineering and Medicine, Proceedings of SPIE 8548, 854842
2. Zhang JY, Ackman JB, Xu HP, Crair MC* (2012). Visual map development depends on the temporal pattern of binocular activity in mice. Nat Neurosci, 15: 298-307 (highlighted in News and Views)
3. Zhang JY, Laiwalla F, Kim JA, Urabe H, Van Wagenen R, Song YK, Connors BW, Zhang F*, Deisseroth K*, Nurmikko AV* (2009). Optical Control and Spatiotemporal Recording of Neural Activity by Waveguide Delivery in Genetically Targeted Brain Tissue. J Neural Eng, 6(5):055007.
4. Zhang JY, Atay T, Nurmikko AV* (2009). Optical detection of brain cell activity using plasmonic gold nanoparticles. Nano Lett, 9(2):519-524 (highlighted in Nature Photonics (2009) Vol. 3(3): 126-127)
5. Zhang JY*, Venkataramani S, Xu H, Song YK, Song HK, Palmore GT, Fallon J, Nurmikko AV (2006). Combined topographical and chemical micropatterns for templating neuronal networks. Biomaterials, 27(33):5734-5739