
Yan-Qin Gao
Professor
Yanqin Gao graduated from Nanjing University in 1983. From 1983-1999, she held positions as an Instructor and later an Associated professor in the Department of Chemistry at Shanghai Medical University. Since 2000, she has been affiliated with the State Key Laboratory of Medical Neurobiology at Fudan University, where she continues her research and academic work. Additionally, from 2018 to 2019, she served concurrently as an Associate professor in the Department of Neurology, University of Pittsburgh School of Medicine.
Professor Gao possesses comprehensive capabilities, including professional expertise, project management, talent training, and a strong sense of dedication and motivation, that enable her to successfully lead and implement proposed research projects. Since 2000, she has focused on neuroscience research, building solid knowledge, professional expertise, and technical proficiency in the fields of ischemic stroke and traumatic brain injury (TBI). Over the past 20 years, she has served as Principal Investigator (PI) or Co-investigator on 16 research grants founded by the National Science Foundation of China (NSFC) and the Chinese/Shanghai Ministry of Science and Technology. Through these roles, she has accumulated extensive experience in grant management and accomplishment, cross-institutional collaboration with other researchers, and Lab administration. Her current researches focus on: 1) Mechanisms underlying the targeted regulation of microglia heterogeneity in neural function remodeling after brain injury; 2) Identification of molecular targets for protecting against brain white matter injury and promoting neurological recovery following stroke and TBI; 3) Pathological mechanism of vascular dementia and the development of Neuroprotective strategies. Professor Gao has published over 140 peer-reviewed scientific papers. Her work has accumulated more than 13,000 citations, with an H-index of 57; notably, mamy of her individual artcles have received nearly 100 citations or more. She Currently serving as Associate Editor of CNS Neurosci & Ther, and Editorial Board Member of Neurobiology of Disease, CNS & Neurological Disorders-Drug Targets and Brain Science. Sadditionally, she acts as a regular reviewer forover 20 prestiqious peer-reviewed journals, including Nat Commun, Adv Sci, Brain, J Neuroinflamm, Theranostics, Sci Bull, Stroke, EBioMedicine, Neurobio Dis, Aging and Disease, Exp Neurol, CNS Neurosic & Therapeutics, iScience.
Address: Room 4-005, Research Buiding B, 138 Yi Xue Yuan Road, Shanghai, 200032
Tel:86-021-54237778
Email:yqgao@@shmu.edu.cn
Preclinical study of neurological remodeling in cerebrovascular disease and traumatic brain injury
Neurobiology
Zhang Z#, Huang S#, Wang Y#, Jiang Z, Liu Z, Wang C, Ji R, Yuan Y, Mao X, Yang K, Niu H, Gao Y*, Zhao J*(2025). Flipping the Switch: MeCP2-Mediated Lactylation Rewires Microglial Metabolism and Inflammation via the HK2/mTOR Axis in Poststroke Neuroinflammation. Adv Sci (Weinh). 22:e13400
Li J#, Wang C#, Zhang Y#, Huang Y, Shi Z, Zhang Y, Wang Y, Chen S, Yuan Yi, Wang H, Miao L*, Gao Y*(2025). Orchestrating the frontline: HDAC3-miKO recruits macrophage reinforcements for accelerated myelin debris clearance after stroke. Theranostics. 15(2): 632-655
Shi Z#, Miao L#, Chen S#, Xiang J, Shi M, Wang Y, Wang Y, Chen X, Xu ZX*, Gao Y*(2024). Reversing Persistent PTEN Activation After Traumatic Brain Injury Fuels Long-Term Axonal Regeneration via Akt/mTORC1 Signaling Cascade. Adv Sci (Weinh). 16: e2410136
Zhang Y#, Li J#, Zhao Y#, Huang Y, Shi Z, Wang H, Cao H, Wang C, Wang Y, Chen D, Meng S, Wang Y, Zhu U, Jiang Y, Gong Y*, Gao Y*(2024). Arresting the bad seed: HDAC3 regulates proliferation of different microglia after ischemic stroke. Sci Adv. 10(10): eade6900
Huang Y, Meng S, Wu B, Shi H, Wang Y, Xiang J, Li J, Shi Z, Wu G, Lyu Y, Jia X, Hu J, Xu ZX*, Gao Y*(2023). HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury. JCI Insight. 8(16): e168919