Rui-Qi Wu

Professor

Principal Investigator

Dr. Ruiqi Wu received her Ph.D. from the University of Chinese Academy of Science in 2014. From 2014 to 2017, she trained as a postdoc at Vanderbilt University Institute of Imaging Science. From 2017 to 2020, she was an associate professor at the Wuhan Institute of Physics and Mathematics, Chinese Academy of Sciences. She has been a principal investigator at the Institute of Brain Science at Fudan University since 2020. She serves as an Editorial Board Member for the international journal “Magnetic Resonance Imaging”, a committee member of the Chinese Association for Chemosensation, and a committee member of the Pain Translational Research Branch of the Shanghai Society for Neuroscience.

Dr. Wu focuses on high-field magnetic resonance imaging methods and their applications. She is interested in investigating the mechanisms of the sensory system and related neuropsychiatric disorders (focusing on pain, epilepsy, and mood disorders), as well as their potential clinical translation strategies, utilizing an integrated approach of MRI, multi-channel electrophysiological recordings, neuromodulation, calcium imaging, artificial intelligence, and circuit tracing. She has published over 30 academic papers, including those in NeuroImage (5), Journal of Neuroscience (4), PLOS Biology, PNAS, Neuron, Cell Discovery, Epilepsia, Nature Communications, European Radiology, and Cerebral Cortex.

Contact  Information

Address: Institutes of Brain Science, Fudan University, 131 Dong Road, Shanghai 200032, China

Email:ruiqiwu@@fudan.edu.cn

Research Directions

  • Functional magnetic resonance imaging methods and applications

Enrollment Major

  • Neurobiology

Selected Publications

  • Tao Y, Zhao Y, Zhu H, Zhang J, Zhong W, Zhu X, Wang Z, Wang N, Yang L*, Xu F, Wu R* (2026). Piriform seizures mediated by the piriform-entorhino-dentate circuit induce brain-wide functional reorganization in mice. Plos Biology. (accepted)

  • Tao Y#, Zhao Y#, Zhong W#, Zhu H, Shao Z, Wu R* (2025). Asymmetric dynamics of GABAergic system and paradoxical responses of GABAergic neurons in piriform seizures. Epilepsia. 66(2):583-598

  • Zhu H#, Tao Y#, Wang S#, Zhu X, Lin K, Zheng N, Chen LM*, Xu F*, Wu R*(2024). fMRI, LFP, and anatomical evidence for hierarchical nociceptive routing pathway between somatosensory and insular cortices. NeuroImage. 289:120549

  • Zhang C#, Tong F#, Zhou B#, He M, Liu S, Du W, Zhou X, Ma Q, Feng T, Chen Z, Yang H, Xu H, Xiao L, Xu Z, Zhu C, Wu R*, Wang Y*, Han Q* (2024). TMC6 Functions as a GPCR-like Receptor Sensing Noxious Heat Via Gαq Signaling. Cell Discovery. 10:66. doi.org/10.1038/s41421-024-00678-9 

  • Wu R, Wang F, Yang PF, Gore JC, Chen LM* (2022). Graph Theory Analysis Identified Two Hubs that Connect Sensorimotor and Cognitive and Cortical and Subcortical Nociceptive Networks in the Non-human Primate. NeuroImage. 257:119244