Prof. Cui-Qing Zhu
Research Directions
The pathogenesis and prevention of Alzheimer's disease
Contact Information
Address： Room 805, Zhidao Building, State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
Tel: +86-21-54237858 Email: cqzhu@shmu.edu.cn
Dr. Cuiqing Zhu received his B.S. degree in Hygiene from (former) Shanghai medical University in 1987. He obtained his M.S. degree in Integrated Chinese and Western Medicine from (former) Shanghai medical University in 1990. He obtained his Ph.D. degree in Integrated Chinese and Western Medicine in 2002 from Fudan University. Since 1990, Dr. Zhu has been working at Shanghai Medical University (presently Fudan University) in Department of Neuroscience, State Key Laboratory of Medical Neurobiology and Institutes for Brain Science. His research has focused on the pathogeneses and prevention treatment of neurodegenerative disorders, especially Alzheimer’s disease.
Enrollment Major
Neurobiology
Research Direction
The pathogenesis and prevention of Alzheimer's disease
Research Work
The mechanisms that mediate stress and brain aging caused the pathological changes of tau
The mechanisms of cellular surface protein DR6 and ATP synthase mediated beta-amyloid neurotoxicity.
Small molecular compounds against Alzheimer's disease
Selected Publications
Shan Y, Wang DD, Xu YX, Wang C, Cao L, Liu YS, Zhu CQ*(2016). Aging as a Precipitating Factor in Chronic Restraint Stress-Induced Tau Aggregation Pathology, and the Protective Effects of Rosmarinic Acid. J Alzheimers Dis. 49(3):829-844
Xu Y, Wang D, Luo Y, Li W, Shan Y, Tan X, Zhu CQ*(2015). Beta amyloid-induced upregulation of death receptor 6 accelerates the toxic effect of N-terminal fragment of amyloid precursor protein. Neurobiol Aging. 36(1):157-168
Xu Y, Zhang P, Wang C, Shan Y, Wang D, Qian F, Sun M, Zhu CQ*(2013). Effect of ginsenoside Rg3 on tyrosine hydroxylase and related mechanisms in the forced swimming-induced fatigue rats. J Ethnopharmacol. 150(1):138-147
Wang HQ, Xu YX, Zhu CQ*(2012). Upregulation of heme oxygenase-1 by acteoside through ERK and PI3 K/Akt pathway confer neuroprotection against beta-amyloid-induced neurotoxicity. Neurotox Res. 21(4):368-378
Yan J, Sun XB, Wang HQ, Zhao H, Zhao XY, Xu YX, Guo JC, Zhu CQ*(2010).Chronic restraint stress alters the expression and distribution of phosphorylated tau and MAP2 in cortex and hippocampus of rat brain. Brain Res. 1347:132-141
