Faculty
Prof. Yu-Qiang Ding

Prof. Yu-Qiang Ding

Principal Investigator


Research Direction
Mechanisms of neural development and neuropsychiatric disorders

Contact Information
Address: 130 Dong An Road, Fudan University, Shanghai China 200032
Tel: 021-54237169  Email: dingyuqiang@vip.163.com

Dr. Yu-Qiang Ding received his MD and PhD degrees from Fourth Military Medical University, China and MD degree by thesis from Kyoto University, Japan. Thereafter, he worked as a postdoc in University of North Carolina at Chapel Hill and Washington University in St. Louis. He became a Principal Investigator at the Institute of Neuroscience, CAS in 2004, and then joined Tongji University with the position of Department Chair of Anatomy and Neurobiology and Director of Laboratory Animal Center in 2009. In 2020, he moved to Fudan University as a full professor in Institutes of Brain Science and Director of Department of Laboratory Animal Science. Dr. Ding was supported by Hundred-Talent Program of CAS, Shanghai Pujiang Program, Program of Shanghai Chief Scientist and National Science Foundation for Distinguished Young Scholars of China.

Dr. Ding also serves as the Chair of Neurotoxin Branch of Chinese Neuroscience Society, a Council Member of Chinese Neuroscience Society and Shanghai Neuroscience Society. He is editorial board member of several journals including “Development, Growth and Differentiation”, Scientific Report, Frontiers in Neuroanatomy, Journal of Chemical Neuroanatomy, Neuropeptides, Journal of Neuroscience Methods, Acta Anatomica Sinica and Chinese Journal of Histochemistry and Cytochemistry.

 

Enrollment Major
Neurobiology

 

Research Work

Dr. Ding’s research interests include 1) the cellular and molecular mechanisms underlying neural development and 2) etiology of neuropsychiatric disorders.

For neural development, the focus of the lab is the cellular and molecular mechanisms underlying cell fate determination, neuronal migration, dendritic development, axon growth and pathfinding in the cerebral cortex and hippocampus. In addition, Dr. Ding is also interested in the function of transcription factors in the development of monoaminergic neurons in the brain stem.

For neuropsychiatric disorders, the focus is the molecular mechanism of monoaminergic neuron-related disorders (depression and fear memory) and biological functions of schizophrenia risk genes.

 

Selected Publications

1. Hu L, Jiang GY, Wang YP, Hu ZB, Zhou BY, Zhang L, Song NN, Huang Y, Chai GD, Chen JY, Lang B, Xu L, Liu JL, Li Y, Wang QX*, Ding YQ*(2022). The role of PTEN in primary sensory neurons in processing itch and thermal information in mice. Cell Rep. 39(3): 110724

2. Chen L, Gong WK, Yang CP, Shao CC, Song NN, Chen JY, Zhou LQ, Zhang KS, Li SG, Huang ZL, Richter-Levin G, Xu L*, Ding YQ*(2021). Pten is a key intrinsic factor regulating raphe 5-HT neuronal plasticity and depressive behaviors in mice. Transl Psychiat. 11(1): 186

3. Huang Y, Huang J, Zhou QX, Yang CX, Yang CP, Mei WY, Zhang L, Zhang Q, Hu L, Hu YQ, Song NN, Wu SX, Xu L*, Ding YQ*(2021). ZFP804A mutant mice display sex-dependent schizophrenia-like behaviors. Mol Psychiatr. 26(6):2514-2532

4. Zhang L*, Song NN, Zhang Q, Mei WY, He CH, Ma PC, Huang Y, Chen JY, Mao BY, Lang B, Ding YQ*(2020). Satb2 is required for the regionalization of retrosplenial cortex. Cell Death Differ. 27(5): 1604-1617

5. Song NN, Ma PC, Zhang Q, Zhang L, Wang HS, Zhang LL, Zhu L, He CH, Mao BY*, Ding YQ*(2020). Rnf220/Zc4h2-mediated monoubiquitylation of Phox2 is required for noradrenergic neuron development. Development. 147(6): dev185199


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