Prof. Yan-Qin Gao

Research Directions
Preclinical study of neurological remodeling in cerebrovascular disease and traumatic brain injury

Contact  Information
Tel:86-021-54237778  E-mail:yqgao@shmu.edu.cn  

Yanqin Gao is graduated from Nanjing University in 1983. From 1983-1999, she worked in Department of Chemistry at Shanghai Medical University as an instructor, associated professor. She joined the State Key Laboratory of Medical Neurobiology at Fudan University since 2000. She concurrently served as an associate professor in the Department of Neurology, University of Pittsburgh School of Medicine from 2018 to 2019.

Professor Gao has the expertise, management, training, dedication and motivation necessary to successfully carry out the proposed research project. She has performed neuroscience research since 2000 and established solid knowledge, expertise and technique in ischemic stroke and traumatic brain injury (TBI) research. As PI or co-Investigator on 15 grants of Chinese National Science Foundation (NSFC) and Chinese/Shanghai Ministry of Science and Technology during last 19 years, she has established extensive experience on grant management and accomplishment, collaboration with other researchers and lab management. Her current researches focus on 1) Mechanism of targeted regulation of microglia polarization on neural function remodeling after brain injury; 2)identify molecular targets to protect against brain white matter injury and promote neurological recovery after stroke and TBI; 3)Pathological mechanism and Neuroprotection of vascular dementia. She has published more than 100 scientific publications. In total, her articles have been cited for more than 7400 times and many of the articles have been cited close to or more than 100 times individually. Professor Gao is an Editorial Board of the Journal of Neurobiology of Disease and the journal of CNS & Neurological Disorders-Drug Targets. She also has been a regular reviewer for more than 20 prominent peer reviewed journals, including Acta Pharmaceutica Sinica B、J Neuroinflamm、Neurosci & Biobehavioral Reviews、 Stroke、EBioMedicine、Neurobio Dis、Aging and Disease、Exp Neurol、CNS Neurosic & Therapeutics, iScience.

Enrollment Major

Selected Publications

1. Wang K, Wang C, Huang Y, Chen D, Wei P, Li J, Shi Z, Zhang Y,Gao YQ*(2022). The role microglial/macrophagic salt-inducible kinase 3 on normal and excessive phagocytosis after transient focal cerebral ischemia. Cell Mol Life Sci  (in press)
2. Chen D, Li JY, Huang YC, Wei PJ, Miao WY, Yang YM,Gao YQ*(2022). Interleukin 13 promotes long-term recovery after ischemic stroke by inhibiting the activation of STAT3. J Neuroinflamm. 19(1): 112
3. Wang Y, Tian M, Tan JY, Pei X, Lu CC, Xin YW, Deng SX, Zhao F,Gao YQ*, Gong Y*(2022). Irisin ameliorates neuroinflammation and neuronal apoptosis through integrin alpha V beta 5/AMPK signaling pathway after intracerebral hemorrhage in mice. J Neuroinflamm. 19(1): 82
4. Li SC, Huang YC, Liu Y, Rocha M, Li XF, Wei PJ, Misilimu D, Luo YH, Zhao J*, Gao YQ*(2021). Change and predictive ability of circulating immunoregulatory lymphocytes in long-term outcomes of acute ischemic stroke. J Cerebr Blood F Met. 41(9):2280-2294
5. Wei PJ, Wang K, Luo C, Huang YC, Misilimu D, Wen HM, Jin P, Li CH, Gong Y*,Gao YQ*(2021). Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury. J Neuroinflamm.18(1): 137

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