Prof. Yan-Qin Gao
Research Directions
Preclinical study of neurological remodeling in cerebrovascular disease and traumatic brain injury
Contact Information
Address： Room 4-005, Research Buiding B, 138 Yi Xue Yuan Road, Shanghai, 200032
Tel：86-021-54237778 E-mail：yqgao@shmu.edu.cn
Yanqin Gao is graduated from Nanjing University in 1983. From 1983-1999, she worked in Department of Chemistry at Shanghai Medical University as an instructor, associated professor. She joined the State Key Laboratory of Medical Neurobiology at Fudan University since 2000. She concurrently served as an associate professor in the Department of Neurology, University of Pittsburgh School of Medicine from 2018 to 2019.
Professor Gao has the expertise, management, training, dedication and motivation necessary to successfully carry out the proposed research project. She has performed neuroscience research since 2000 and established solid knowledge, expertise and technique in ischemic stroke and traumatic brain injury (TBI) research. As PI or co-Investigator on 15 grants of Chinese National Science Foundation (NSFC) and Chinese/Shanghai Ministry of Science and Technology during last 20 years, she has established extensive experience on grant management and accomplishment, collaboration with other researchers and lab management. Her current researches focus on 1) Mechanism of targeted regulation of microglia polarization on neural function remodeling after brain injury; 2) identify molecular targets to protect against brain white matter injury and promote neurological recovery after stroke and TBI; 3）Pathological mechanism and Neuroprotection of vascular dementia. She has published more than 100 scientific publications. In total, her articles have been cited for more than 7700 times, H-index is 50, and many of the articles have been cited close to or more than 100 times individually. Professor Gao is an Editorial Board of the Journal of Neurobiology of Disease, CNS & Neurological Disorders-Drug Targets, and Brain Sci. She also has been a regular reviewer for more than 20 prominent peer reviewed journals, including Adv Sci, Brain, J Neuroinflamm, Stroke, EBioMedicine, Neurobio Dis、Aging and Disease、Exp Neurol、CNS Neurosic & Therapeutics, iScience.
Enrollment Major
Neurobiology
Selected Publications
1. Zhang Y, Li JY, Zhao YF, Huang YC, Shi ZY, Wang HL, Cao H, Wang CR, Wang YA, Chen D, Chen SN, Meng S, Wang YF, Zhu YY, Jiang Y, Gong Y*, Gao Y*(2024). Arresting the bad seed: HDAC3 regulates proliferation of different microglia after ischemic stroke. Sci Adv. 10(10): eade6900
2. Huang Y, Meng S, Wu B, Shi H, Wang Y, Xiang J, Li J, Shi Z, Wu G, Lyu Y, Jia X, Hu J, Xu ZX*, Gao Y*(2023). HSPB2 facilitates neural regeneration through autophagy for sensorimotor recovery after traumatic brain injury. JCI Insight. 8(16):e168919
3. Meng S, Cao H, Huang Y, Shi Z, Li J, Wang Y, Zhang Y, Chen S, Shi H*, Gao Y*(2023). ASK1-K716R reduces neuroinflammation and white matter injury via preserving blood-brain barrier integrity after traumatic brain injury. J Neuroinflamm. 20(1):244
4. Chen D, Li JY, Huang YC, Wei PJ, Miao WY, Yang YM, Gao Y*(2022). Interleukin 13 promotes long-term recovery after ischemic stroke by inhibiting the activation of STAT3. J Neuroinflamm. 19(1): 112
5. Wei P, Wang K, Luo C, Huang YC, Misilimu D, Wen H, Jin P, Li CH, Gong Y*, Gao Y*(2021). Cordycepin confers long-term neuroprotection via inhibiting neutrophil infiltration and neuroinflammation after traumatic brain injury. J Neuroinflamm. 18(1): 137
