Prof. Ying Zhu
Principal Investigator
Research Directions
1. Functional genomics of human brain development, evolution, and disorders
2. Computational biology and bioinformatics
Contact Information
Address: Third floor, West Building 6, 130 Dong’an Road, Institutes of Brain Science, Fudan University, Shanghai China 200032
Tel：021-54237688 Email: ying_zhu@fudan.edu.cn
Dr. Ying Zhu received her B.S. degree in Biology from Tsinghua University in 2008 and Ph.D. degree in Neurobiology from Yale University in 2014. From 2014 to 2017, she worked as a joint postdoc associate in the Department of Neurobiology and the Department of Biostatistics at Yale University. Since 2017, she worked as an Associate Research Scientist in the Department of Biostatistics, until she joined the institute of brain science in Fudan University in 2019. Her work has been published on top journals including Nature and Science.
Enrollment Major
Neurobiology
Research Direction
1. Decoding the molecular and cellular bases of brain development, evolution and disorders, through high throughput sequencing and bioinformatics analysis.
2. Development of bioinformatics methods for high-throughput sequencing data analysis; computational modeling of complex biological systems.
Selected Publications
1. Zhou Y, He W, Hou WZ, Zhu Y# (2024). Pianno: a probabilistic framework automating semantic annotation for spatial transcriptomics. Nature Communications. 15 (1), 2848
2. Li P*, Wei J*, Zhu Y# (2023). CellGO: a novel deep learning-based framework and webserver for cell-type-specific gene function interpretation. Briefings in Bioinformatics. 25 (1), bbad417
3. Tong SY, Fan K, Zhou ZW, Liu LY, Zhang SQ, Fu Y, Wang GZ, Zhu Y#, Yu YC# (2022). MvPPT: a highly efficient and sensitive pathogenicity prediction tool for missense variants. Genomics, Proteomics & Bioinformatics. S1672-0229(22)00091-2 (#Co-corresponding author)
4. Zhu Y#, Sousa AMM#, Gao T#, Skarica M#, Li M#, Santpere G, Esteller-Cucala P, Juan D, Ferrández-Peral L, Gulden FO, Yang M, Miller DJ, Marques-Bonet T, Kawasawa YI, Zhao H, Sestan N* (2018). Spatio-temporal transcriptomic divergence across human and macaque brain development. Science. 362(6420):eaat8077. (*Co-first author)
5. Sousa AMM#, Zhu Y#, Raghanti MA, Kitchen RR, Onorati M, Tebbenkamp ATN, Stutz B, Meyer KA, Li M, Kawasawa YI, Liu F, Perez RG, Mele M, Carvalho T, Skarica M, Gulden FO, Pletikos M, Shibata A, Stephenson AR, Edles MK, Ely JJ, Elsworth JD, Horvath TL, Hof PR, Mane SM, Noonan JP, State MW, Lein ES, Knowles JA, Marques-Bonet T, Sherwood CC, Gerstein MB, Sestan N* (2017). Molecular and cellular reorganization of neural circuits in the human lineage. Science. 358, 1027-1032. (*Co-first author)
