Prof. Jian-Hong Zhu

Principal Investigator

Research Directions
Development and stem cell biology, brain regenerative medicine, consciousness and coma, neuro-oncology, neurosurgery
Contact  Information

Address: Huashan Hospital, Shanghai Medical College, Fudan University, 12 Middle Wulumuqi Road, Shanghai 200040, China
Tel:86-021-52888274  E-mail: jzhu@fudan.edu.cn


Dr. Jianhong Zhu is the Professor of Neurosurgery at Fudan University Huashan Hospital and Deputy Director of National Key Laboratory for Medical Neurobiology. Professor Zhu received his M.D. from Suzhou University and Ph.D. degree from Berlin-Humboldt University, Germany. He received his postdoctoral training at the Nippon Medical School in Tokyo, Japan. Dr. Zhu was a Kesley Welch Fellow at Brigham & Women's Hospital and Children's Hospital, Harvard Medical School, Boston,US. Dr. Zhu is one of expertise in neural stem cell research. He led the first team to successfully grow human neural stem cells from open brain trauma in the laboratory, and used these to repair the damaged brains of head-injury victims in Fudan University Huashan Hospital. He received the Young Neurosurgeon Award of the World Federation of Neurosurgical Societies (WFNS). He served on the executive committee as the treasurer for Asia-Australiasian Society of Neurological Surgery (AANS)and the vice president for Chinese Society of Neuro-Oncology (CSNO), the vice president for Shanghai Neuroscience Socienty and as editorial board member of《Regenerative Medicine》in UK and《Reviews on Clinical Trials》in US.


Enrollment Major

Research Direction
Development and stem cell biology, brain regenerative medicine, consciousness and coma, neuro-oncology, neurosurgery

Selected Publications

1. Wang ZF, Wang F, Zhong JJ, Zhu TM, Zheng YT, Zhao T, Xie Q, Ma FK, Li RG, Tang QS, Xu F, Tian XY, Zhu JH*(2020). Using apelin-based synthetic Notch receptors to detect angiogenesis and treat solid tumors. Nat Commun. 11(1):2163

2. Wang ZF, Zheng YT, Wang F, Zhong JJ, Zhao T, Xie Q, Zhu TM, Ma FK, Tang QS, Zhou B, Zhu JH*(2020). Mfsd2a and Spns2 are essential for sphingosine-1-phosphate transport in the formation and maintenance of the blood-brain barrier. Sci Adv. 6(22): eaay8627

3. Xie Q, Zeng J, Zheng YT, Li TW, Ren JW, Chen KZ, Zhang Q, Xie R, Xu F, Zhu JH*(2021). Mitochondrial Transplantation Attenuates Cerebral Ischemia-Reperfusion Injury: Possible Involvement of Mitochondrial Component Separation. Oxid Med Cell Longev. 2021: 1006636

4. Wang T, Sha HY*, Ji DM, Zhang HL, Chen DW, Cao YX, Zhu JH* (2014). Polar body genome transfer for preventing the transmission of inherited mitochondrial disease. Cell. 157(7): 1591-1604

5. Zhu JH*, Zhou L, Ge F, Wu X (2006). Tracking neural stem cells in brain trauma patients. New Engl J Med. 355: 2736-2738


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