Prof. Bing-Qiao Zhao
Principal Investigator
Research Directions
The cellular and molecular responses to cerebral ischemia and thrombolytic-induced hemorrhage; The mechanisms that mediate angiogenesis after brain injury such as stroke
Contact Information
Address: State Key Laboratory of Medical Neurobiology, Fudan University, 131 Dongan Road,Shanghai 200032, China
Tel：+86-21-54237884 Email: bingqiaoz@fudan.edu.cn
Dr. Zhao received his Ph.D. from Hamamatsu University School of Medicine, Japan, and did his postdoctoral work at Harvard Medical School. Dr. Zhao joined Fudan University in 2009. The focus of his research is ischemic stroke and intracerebral hemorrhage. The group studies the relationships of neurovascular components to neurons after brain injury and self-repair using a combination of animal models, cellular, molecular and biological approaches.
Enrollment Major
Neurobiology
Research Direction
I) The cellular and molecular responses to cerebral ischemia and thrombolytic-induced hemorrhage.
II) The mechanisms that mediate angiogenesis after brain injury such as stroke.
Selected Publications
1. Yu H, Luo H, Chang L, Wang S, Geng X, Kang L, Zhong Y, Cao Y, Wang R, Yang X, Zhu Y, Shi MJ, Hu Y, Liu Z, Yin X, Ran Y, Yang H,Fan W*,Zhao BQ* (2022). The NEDD8-activating enzyme inhibitor MLN4924 reduces ischemic brain injury in mice. Proc Natl Acad Sci U S A. 119(6):e2111896119.
2. Wang R, Zhu Y, Liu Z, Chang L, Bai X, Kang L, Cao Y, Yang X, Yu H, Shi MJ, Hu Y,Fan W*,Zhao BQ* (2021). Neutrophil extracellular traps promote tPA-induced brain hemorrhage via cGAS in mice with stroke. Blood. 138(1):91-103. (Cover story)
3. Kang L, Yu H, Yang X, Zhu Y, Bai X, Wang R, Cao Y, Xu H, Luo H, Lu L, Shi MJ, Tian Y, Fan W*, Zhao BQ* (2020). Neutrophil extracellular traps released by neutrophils impair revascularization and vascular remodeling after stroke.Nature Communications. 11(1):2488.
4. Wang L, Fan W*, Cai P, Fan M, Zhu X, Dai Y, Sun C, Cheng Y, Zheng P, Zhao BQ*(2013). Recombinant ADAMTS13 reduces tissue plasminogen activator-induced hemorrhage after stroke in mice .Annals of Neurology.73(2):189-198.
