Prof. Yun Wang

Principal Investigator

Research Directions
Cellular mechanism and neuropharmacology of neurological disorders including epilepsy and Alzheimer's disease.
Contact  Information
Address: Institutes of Brain Science, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
Tel：54237594; E-mail: yunwang@fudan.edu.cn

Dr Yun Wang is Graduated from Fudan University in 1987, and been awarded his PhD degree in neurophysiology in 1995 from Glasgow University supported by the Wellcome Trust Studentship (1989-1992). Between 1993 and 2000, he served as a postdoc research assistant in Department of Physiology (1993-1998) and a research fellow in Pharmacology (1998-2000) in University College London before he joined in Lilly Research Centre (UK), Eli Lilly Company as a senior scientist and group leader in 2000. Dr Wang was recruited back to China in 2005 to take a position as a Chief Scientific Officer in Central Research Institute, Shanghai Pharm Co Ltd, before he moved back to Fudan University became a Principle Investigator in Fudan University in 2007. He has been currently appointed as a professor and senior principle investigator by the Institutes of Brain Science, Fudan University, Shanghai, China. Dr Wang is currently a member of the editorial board of several SCI journals, and he has published 70+ SCI papers in varies scientific journals including Nature Neuroscience, PNAS, Journal of Physiology, British Journal Pharmacology, etc.  Dr Wang has been supported by the fundings from Chinese Nature Science Foundation, Science and Technology Commission of Shanghai Municipality, Shanghai Pujiang Program for Talented People.

Enrollment Major
Neurobiology

Research Direction
Cellular mechanism and neuropharmacology of neurological disorders

Selected Publications       

1． Yu J, Wang G, Chen Z, Wan L, Zhou J, Cai J, Liu X*, Wang Y* (2023). Deficit of PKHD1L1 in the dentate gyrus increases seizure susceptibility in mice. Hum Mol Genet. 32(3):506-519

2． Chen L, Yu J, Wan L, Wang G, Hu Z, Wu Z, Qian B, Zhao X*, Zhang J, Liu X*, Wang Y* (2022). Furosemide prevents membrane KCC2 downregulation during convulsant stimulation in the hippocampus. IBRO Neuroscience Reportsz. 12: 355-365

3． Shi W*, Wei X, Wang X, Du S, Liu W, Song J, Wang Y* (2019). Perineuronal nets protect long-term memory by limiting activity-dependent inhibition from parvalbumin interneurons. PNAS. 116(52): 27063-27073 

4． Sang S, Pan X, Chen Z, Zeng F, Pan S, Liu H, Jin L, Fei G, Wang C, Ren S, Jiao F, Bao W, Zhou W, Guan Y, Zhang Y, Shi H, Wang Y, Yu X, Wang Y*, Zhong C* (2018). Thiamine diphosphate reduction strongly correlates with brain glucose hypometabolism in Alzheimer's disease, while amyloid deposition does not. Alzheimer's Research & Therapy. 10:26

5． Cheng L, Duan B, Huang T, Zhang Y, Chen Y, Britz O, Garcia-Campmany L, Ren X, Vong L, Lowell BB, Goulding M, Wang Y*, Ma Q* (2017). Identification of spinal circuits required to transmit touch-evoked dynamic mechanical pain. Nature Neuroscience. 26(2):804-817