Prof. Zhi-Li Huang

Prof. Zhi-Li Huang

Principal Investigator


Research Direction
Neurobiology of sleep and insomnia;Pharmacology of hypnotics and sedatives
Contact Information
Address:State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
Tel: 021-54237043  E-mail: huangzl@fudan.edu.cn

Dr. Zhi-Li Huang graduated from Wannan Medical College in 1985, and was awarded two Sasakawa Fellowships to receive his PhD from Ehime University of Japan in 1999. Thereafter, he worked as a postdoctoral fellow for Japan Society for Promotion of Science, a senior research scientist and vice-head of Dept. of Molecular Behavioral Biology in the Osaka Bioscience Institute, Japan. In 2005, he became a Principal Investigator of Sleep Research Program, State Key Laboratory of Medical Neurobiology and Brain Science Institute, and Professor, Department of Pharmacology of Shanghai Medical College, Fudan University.

His research interest is the hypothalamic regulation of sleep-wake cycle with focus on the histaminergic system. He published a series of original and review papers in Nature Neuroscience, PNAS, J Neuroscience, Progress in Neurobiology, and so on. He serves as a reviewer for more than 10 international journals such as PNAS, J Neuroscience, J Neurochemistry and Neuropharmacology. Based on his contributions to basic sleep research, he received Japan Sleep Research Award in 2005 and the grant from China National Fundation for Distinguished Young Scientists in 2006.


Enrollment Major


Selected Publications

  1. Zhang Z#, Liu WY#, Diao YP, Xu W, Zhong YH, Zhang JY, Lazarus M, Liu YY, Qu WM*, Huang ZL*(2019). Superior colliculus GABAergic neurons are essential for acute dark-induction of wakefulness in mice. Current Biology. 29(4):637-644

  2. Wu YE, Enoki R*, Oda Y, Huang ZL*, Honma K, Honma S (2018). Ultradian Calcium Rhythms in the Paraventricular Nucleus and Subparaventricular Zone in the Hypothalamus. Proc Natl Acad Sci U S A.115(40):E9469-E9478 

  3. Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM*, Huang ZL*(2018). Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D1 receptors. Nature Communications. 9(1):1576

  4. Yang SR*, Hu ZZ, Luo YJ, Zhao YN, Sun HX, Yin D, Wang CY, Yan YD, Wang DY, Yuan XS, Ye CB, Guo W, Qu WM, Cherasse Y, Lazarus M, Ding YQ, Huang ZL*(2018). The rostromedial tegmental nucleus is essential for non-rapid eye movement sleep. PLoS Biology. 16(4):e2002909

  5. Zhang Z, Wang HJ, Wang DR, Qu WM*, Huang ZL*(2017). Red light at intensities above 10 lx alters sleep-wake behavior in mice. Light: Science & Applications. e16231

138 Yixueyuan Road, Shanghai 200032, China; Tel:021-54237641   

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