Prof. Zhi-Li Huang

Principal Investigator


Research Direction
Neurobiology of sleep and insomnia;Pharmacology of hypnotics and sedatives
Contact Information
Address:State Key Laboratory of Medical Neurobiology, Fudan University, 138 Yixueyuan Road, Shanghai 200032, China
Tel: 021-54237043  E-mail: huangzl@fudan.edu.cn

Dr. Zhi-Li Huang graduated from Wannan Medical College in 1985, and was awarded two Sasakawa Fellowships to receive his PhD from Ehime University of Japan in 1999. Thereafter, he worked as a postdoctoral fellow for Japan Society for Promotion of Science, a senior research scientist and vice-head of Dept. of Molecular Behavioral Biology in the Osaka Bioscience Institute, Japan. In 2005, he became a Principal Investigator of Sleep Research Program, State Key Laboratory of Medical Neurobiology and Brain Science Institute, and Professor, Department of Pharmacology of Shanghai Medical College, Fudan University.

His research interest is the hypothalamic regulation of sleep-wake cycle with focus on the histaminergic system. He published a series of original and review papers in Nature Neuroscience, PNAS, J Neuroscience, Progress in Neurobiology, and so on. He serves as a reviewer for more than 10 international journals such as PNAS, J Neuroscience, J Neurochemistry and Neuropharmacology. Based on his contributions to basic sleep research, he received Japan Sleep Research Award in 2005 and the grant from China National Fundation for Distinguished Young Scientists in 2006.


Enrollment Major


Selected Publications

1. Dong H, Chen ZK, Guo H, Yuan XS, Liu CW, Qu WM*, Huang ZL*(2022). Striatal neurons expressing dopamine D1 receptor promote wakefulness in mice. Curr Biol. 32(3): 600-613

2. Li YD, Luo YJ, Xu W, Ge J, Cherasse Y, Wang YQ, Lazarus M, Qu WM*, Huang ZL*(2021). Ventral pallidal GABAergic neurons control wakefulness associated with motivation through the ventral tegmental pathway. Mol Psychiatr. 26(7): 2912-2928

3. Bao WW, Xu W, Pan GJ, Wang TX, Han Y, Qu WM, Li WX*, Huang ZL*(2021). Nucleus accumbens neurons expressing dopamine D1 receptors modulate states of consciousness in sevoflurane anesthesia. Curr Biol. 31(9): 1893-1902.e5

4. Zhang Z, Liu WY, Diao YP, Xu W, Zhong YH, Zhang JY, Lazarus M, Liu YY, Qu WM*, Huang ZL*(2019). Superior colliculus GABAergic neurons are essential for acute dark induction of wakefulness in mice. Curr Biol. 29(4): 637-644

5. Luo YJ, Li YD, Wang L, Yang SR, Yuan XS, Wang J, Cherasse Y, Lazarus M, Chen JF, Qu WM*, Huang ZL*(2018). Nucleus accumbens controls wakefulness by a subpopulation of neurons expressing dopamine D-1 receptors. Nat Commun. 9: 1576

138 Yixueyuan Road, Shanghai 200032, China; Tel:021-54237641   

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